Author

M. J. Geer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. J. Barr· 1 shared A. Jouppila· 1 shared A. Mazharian· 1 shared B. G. Neel· 1 shared C. Geh· 1 shared C. W. Smith· 1 shared D. J. Ogg· 1 shared D. Semeniak· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. J. Barr

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genome-wide CRISPR/Cas9 Screens Reveal Shared and Bespoke Mechanisms of Resistance to SHP2 inhibition

W. Wei, M. J. Geer, X. Guo, I. Dolgalev, N. E. Sanjana, B. G. Neel

This study identifies genes conferring resistance to SHP2 inhibitors through CRISPR screens and shows their roles in reactivating ERK signaling in cancer cells.

bioRxiv · Aug 26, 2022 · PreprintCancer Biology

Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

T. Vögtle, S. Sharma, J. Mori, Z. Nagy, D. Semeniak, M. J. Geer, C. W. Smith, J. Lane, S. Pollack, R. Lassila, A. Jouppila, A. J. Barr, D. J. Ogg, T. D. Howard, H. J. McMiken, , Y. A. Senis

This study identifies heparan sulfate as a critical regulator of G6b-B, showing it inhibits platelet and megakaryocyte function through Shp1/Shp2 signaling.

bioRxiv · Mar 25, 2019Biochemistry