Author

M. Katan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Breeze· 1 shared A. Fleming· 1 shared A. J. D. Snow· 1 shared B. Farrell· 1 shared B. J. Lane· 1 shared C. Dominguez Conde· 1 shared E. Atkinson· 1 shared E. Dann· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. Breeze

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell-free expression and SMA copolymer encapsulation of a functional receptor tyrosine kinase disease variant, FGFR3-TACC3

A. J. D. Snow, T. Wijesiriwardena, B. J. Lane, B. Farrell, P. C. Dowdle, M. Katan, s. P. muench, A. Breeze

This paper expresses and functionally characterizes the oncogenic RTK FGFR3-TACC3 using cell-free protein expression, achieving significant kinase activity.

bioRxiv · Jun 4, 2024Biochemistry

Cells of the human intestinal tract mapped across space and time

R. Elmentaite, N. Kumasaka, H. W. King, K. Roberts, M. Dabrowska, S. Pritchard, L. Bolt, S. F. Vieira, L. Mamanova, N. Huang, I. Goh Kai'En, E. Stephenson, J. Engelbert, R. A. Botting, A. Fleming, , S. A. Teichmann

The paper maps human intestinal cell lineages across development and disease, identifying new cell types and functions related to inflammation and immunity.

bioRxiv · Apr 7, 2021Cell Biology

Targeting the Src pathway enhances the efficacy of selective FGFR inhibitors in cancers with FGFR3 alterations

N. C. Lima, E. Atkinson, T. D. Bunney, M. Katan, P. H. Huang

This study shows that combining Src pathway inhibitors with FGFR inhibitors improves efficacy in cancers with FGFR3 mutations by overcoming intrinsic resistance.

bioRxiv · Apr 4, 2020Cancer Biology