Author

L. Bolt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

L. Mamanova· 4 shared K. B. Meyer· 3 shared K. Polanski· 3 shared K. Saeb-Parsy· 3 shared N. Huang· 3 shared S. A. Teichmann· 3 shared K. T. Mahbubani· 2 shared L. Richardson· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersCell Biology

L. Mamanova

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age

S. B. Wells, D. Rainbow, M. Mark, P. P. A. S. Szabo, C. Ergen, A. R. Maceiras, D. P. Caron, E. Rahmani, E. Benuck, V. V. P. Amiri, D. Chen, A. Wagner, S. K. Howlett, L. B. Jarvis, K. L. Elli, , N. Yosef

The paper profiles immune cell RNA and protein expression across tissues and age to identify tissue-specific and age-related immune signatures.

Nature Immunology · Aug 13, 2025Peer-reviewedImmunology

The emergence of goblet inflammatory or ITGB6hi nasal progenitor cells determines age-associated SARS-CoV-2 pathogenesis

M. Woodall, A.-M. Cujba, K. B. Worlock, K.-M. Case, T. Masonou, M. Yoshida, K. Polanski, N. Huang, R. G. Lindeboom, L. Mamanova, L. Bolt, L. Richardson, S. Ellis, M. Palor, T. Burgoyne, , C. M. Smith

The study identifies age-related differences in nasal epithelial cell responses to SARS-CoV-2 infection, showing distinct progenitor cell dynamics in children and elderly.

bioRxiv · Jan 16, 2023 · PreprintCell Biology

A spatial multi-omics atlas of the human lung reveals a novel immune cell survival niche

E. Madissoon, A. J. Oliver, V. Kleshchevnikov, A. Wilbrey-Clark, K. Polanski, A. E. Ribeiro Orsi, L. Mamanova, L. Bolt, J. P. Pett, N. Huang, R. Elmentaite, N. Richoz, P. He, M. Dabrowska, E. Tuck, , K. B. Meyer

The paper creates a spatial multi-omics lung atlas identifying novel cell types and a survival niche for IgA-secreting plasma cells in submucosal glands.

bioRxiv · Nov 26, 2021 · PreprintCell Biology

Cells of the human intestinal tract mapped across space and time

R. Elmentaite, N. Kumasaka, H. W. King, K. Roberts, M. Dabrowska, S. Pritchard, L. Bolt, S. F. Vieira, L. Mamanova, N. Huang, I. Goh Kai'En, E. Stephenson, J. Engelbert, R. A. Botting, A. Fleming, , S. A. Teichmann

The paper maps human intestinal cell lineages across development and disease, identifying new cell types and functions related to inflammation and immunity.

bioRxiv · Apr 7, 2021Cell Biology