Author

M. L. MacDonald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Amalric· 1 shared A. N. Grumet· 1 shared A. R. Cole· 1 shared A. Uboveja· 1 shared A. Valvezan· 1 shared B. Yang· 1 shared C. Happe· 1 shared C. J. Brown· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Amalric

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Author profile →

2 papers

Recent·Most cited

ATR promotes mTORC1 activity via de novo cholesterol synthesis

N. K. Tangudu, A. N. Grumet, R. Fang, R. Buj, A. R. Cole, A. Uboveja, A. Amalric, B. Yang, Z. Huang, C. Happe, M. Sun, S. L. Gelhaus, M. L. MacDonald, N. Hempel, N. W. Snyder, , K. M. Aird

This study shows ATR enhances mTORC1 activity through cholesterol synthesis via LSS, independent of CHK1 and TSC, and this effect is amplified in p16-deficient cells.

bioRxiv · Oct 27, 2023Cell Biology

Glycoproteome Analysis of Human Serum and Brain Tissue

C. J. Brown, K. T. Grassmyer, M. L. MacDonald, D. E. Clemmer, J. C. Trinidad

The paper develops a glycoproteome analysis method to identify glycopeptides in human serum and brain tissue, revealing tissue-specific glycan diversity and biosynthetic pathway differences.

bioRxiv · May 23, 2019 · PreprintBiochemistry