Author

M. Linster

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L.-F. Wang· 3 shared S. Kalimuddin· 3 shared A. Bertoletti· 2 shared A. Chia· 2 shared A. T. Tan· 2 shared D. Lye· 2 shared G. J. Smith· 2 shared J. Jayakumar· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersImmunology

L.-F. Wang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Spike independent infection of human coronavirus 229E in bat cells

M. G. Mah, M. Linster, D. H. Low, Z. Yan, J. Jayakumar, F. Samsudin, F. Y. Wong, P. J. Bond, I. H. Mendenhall, Y. C. Su, G. J. Smith

This study shows that human coronavirus 229E can infect bat cells without using its spike protein, revealing a spike-independent infection mechanism in bats.

bioRxiv · Sep 18, 2021Microbiology

Early induction of SARS-CoV-2 specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients

A. T. Tan, M. Linster, C. Tan, N. Le Bert, W. Chia, K. Kunasegaran, Y. Zhuang, C. Y. Tham, A. Chia, G. J. Smith, B. E. Young, S. Kalimuddin, J. G. Low, D. Lye, L.-F. Wang, A. Bertoletti

The paper examines the relationship between SARS-CoV-2 specific T cell responses and disease severity in COVID-19 patients, finding that early T cell induction correlates with mild disease and faster viral clearance.

bioRxiv · Oct 15, 2020Immunology

Different pattern of pre-existing SARS-COV-2 specific T cell immunity in SARS-recovered and uninfected individuals

N. Le Bert, A. T. Tan, K. Kunasegaran, C. Y. L. Tham, M. Hafezi, A. Chia, M. Chng, M. Lin, N. Tan, M. Linster, W. N. Chia, M. I.-C. Chen, L.-F. Wang, E. E. Ooi, S. Kalimuddin, , A. Bertoletti

The paper compares pre-existing SARS-CoV-2 specific T cell immunity in SARS-recovered and uninfected individuals, finding differential T cell immunodominance patterns.

bioRxiv · May 26, 2020Immunology

Discovery of a 382-nt deletion during the early evolution of SARS-CoV-2

Y. Su, D. Anderson, B. Young, F. Zhu, M. Linster, S. Kalimuddin, J. Low, Z. Yan, J. Jayakumar, L. Sun, G. Yan, I. Mendenhall, Y.-S. Leo, D. Lye, L.-F. Wang, G. Smith

The paper identifies a 382-nt deletion in SARS-CoV-2 ORF8 from Singapore patients, which enhances N gene transcription and may contribute to viral attenuation.

bioRxiv · Mar 11, 2020 · PreprintMicrobiology