Author

M. Nagae

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

S. Yamasaki· 2 shared C. Guenther· 1 shared D. Mori· 1 shared D. Motooka· 1 shared E. E. Nakayama· 1 shared E. Ishikawa· 1 shared G. D. Brown· 1 shared H. Arase· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

S. Yamasaki

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Author profile →

2 papers

Recent·Most cited

Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2

S. Haji, T. Ito, C. Guenther, M. Nakano, T. Shimizu, D. Mori, Y. Chiba, M. Tanaka, S. K. Mishra, J. A. Willment, G. D. Brown, M. Nagae, S. Yamasaki

This study identifies human Dectin-1 as a ligand for CLEC-2, showing its O-glycosylation enables it to function as a physiological ligand for immune regulation.

eLife · Dec 8, 2022Peer-reviewedImmunology

Identification, crystallization and epitope determination of public TCR shared and expanded in COVID-19 patients

X. Lu, Y. Hosono, S. Ishizuka, M. Nagae, E. Ishikawa, D. Motooka, Y. Ozaki, N. Sax, R. Shinnakasu, T. Inoue, T. Onodera, T. Matsumura, M. Shinkai, T. Sato, S. Nakamura, , S. Yamasaki

The paper identifies and crystallizes public TCRs from SARS-CoV-2-specific Tfh cells in COVID-19 patients, showing they recognize conserved spike epitopes and cross-react with symbiotic bacteria.

bioRxiv · Mar 23, 2021Immunology