Author

J. A. Willment

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Organism:multiple species· 1

Frequent Co-Authors

G. D. Brown· 3 shared A. J. Crossen· 1 shared A. S. Palma· 1 shared C. Guenther· 1 shared C. M. Reardon· 1 shared D. M. Reid· 1 shared D. Mori· 1 shared G. N. Kwaku· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

G. D. Brown

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Author profile →

3 papers

Recent·Most cited

Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing

J. L. Reedy, K. N. Jensen, A. J. Crossen, K. J. Basham, R. A. Ward, C. M. Reardon, H. B. Harding, O. W. Hepworth, P. Simaku, G. N. Kwaku, K. Tone, J. A. Willment, D. M. Reid, M. H. Stappers, G. D. Brown, , J. M. Vyas

This study shows fungal melanin blocks chemokine secretion and calcium fluxing in airway epithelial cells, reducing neutrophil recruitment to the airway.

bioRxiv · Mar 28, 2023 · PreprintImmunology

Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2

S. Haji, T. Ito, C. Guenther, M. Nakano, T. Shimizu, D. Mori, Y. Chiba, M. Tanaka, S. K. Mishra, J. A. Willment, G. D. Brown, M. Nagae, S. Yamasaki

This study identifies human Dectin-1 as a ligand for CLEC-2, showing its O-glycosylation enables it to function as a physiological ligand for immune regulation.

eLife · Dec 8, 2022Peer-reviewedImmunology

Mannan detecting C-type lectin receptor probes recognise immune epitopes with diverse chemical, spatial and phylogenetic heterogeneity in fungal cell walls

I. Vendele, J. A. Willment, L. M. Silva, A. S. Palma, W. Chai, Y. Liu, T. Feizi, M. H. T. Stappers, G. D. Brown, N. A. R. Gow

The paper maps mannan-specific C-type lectin receptor (CTL) epitopes in fungal cell walls, revealing spatial, chemical, and phylogenetic diversity in immune recognition.

bioRxiv · Jun 19, 2019Microbiology