NOTCH-YAP1/TEAD-DNMT1 axis regulates hepatocytereprogramming into intrahepatic cholangiocarcinoma
S. Hu, L. M. Molina, J. Tao, S. Liu, M. Hassan, S. Singh, M. Poddar, A. Bell, D. Sia, M. Oertel, R. Raeman, K. Nejak-Bowen, A. Singhi, J. Luo, S. P. Monga, S. Ko
The paper identifies a NOTCH-YAP1/TEAD-DNMT1 axis that drives hepatocyte reprogramming into intrahepatic cholangiocarcinoma and reveals its role in tumor development.
bioRxiv · Dec 3, 2020 · PreprintCancer Biology