Author

M. Osaki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

F. Okada· 2 shared H. Kugoh· 2 shared T. Ohira· 2 shared D. Inaoka· 1 shared D. Takamatsu· 1 shared F. Maruyama· 1 shared G. Goyette-Desjardins· 1 shared H. Kojima· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

F. Okada

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Soluble CTLA-4 mainly produced by Treg cells inhibits type 1 inflammation without hindering type 2 immunity to allow for inflammation resolution

M. Osaki, S. Sakaguchi

This study shows that soluble CTLA-4 from Treg cells inhibits type 1 inflammation while preserving type 2 immunity, aiding inflammation resolution.

bioRxiv · May 26, 2023Immunology

Endothelial metastasis-associated protein 1 (MTA1) is an essential molecule for angiogenesis

M. Osaki, M. Ishikawa, N. Uno, T. Ohira, H. Kugoh, F. Okada

This study shows that MTA1 is essential for angiogenesis by promoting tube formation in endothelial cells and that its pathway differs from the VEGF-VEGF receptor 2 pathway.

bioRxiv · Apr 15, 2021 · PreprintCell Biology

Capsular polysaccharide switching in Streptococcus suis modulates host cell interactions and virulence

M. Okura, J.-P. Auger, T. Shibahara, G. Goyette-Desjardins, M.-R. Van Calsteren, F. Maruyama, M. Kawai, M. Osaki, M. Segura, M. Gottschalk, D. Takamatsu

This study shows that serotype switching in Streptococcus suis can differentially affect host cell interactions and virulence, with some serotypes increasing or decreasing pathogenicity.

bioRxiv · Oct 12, 2020Microbiology

PITX1 protein interacts with ZCCHC10 to regulate hTERT mRNA transcription

T. Ohira, H. Kojima, Y. Kuroda, D. Inaoka, M. Osaki, H. Wanibuchi, F. Okada, M. Oshimura, H. Kugoh

The paper identifies a ZCCHC10-PITX1 complex that suppresses hTERT transcription, contributing to telomerase regulation in melanoma.

bioRxiv · May 16, 2019Cancer Biology

M. Osaki · henhao