Cancer BiologybioRxiv
Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts
P. van der Lelij, S. Lieb, J. Jude…·M. P. Petronczki
The paper identifies a synthetic lethal relationship between STAG1 and STAG2 in cancers, showing STAG1 inactivation selectively targets STAG2-mutated cancer cells.
DOI 10.7554/elife.26980