Author

J. Jude

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

J. Zuber· 2 shared A. Cantoran-Garcia· 1 shared A. Schlattl· 1 shared C. Bernardini· 1 shared C. P. Santos· 1 shared F. R. Traube· 1 shared F. X. Real· 1 shared G. A. Versteeg· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

J. Zuber

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CRISPR gene and transcriptome engineering (CRISPRgate) improves loss-of-function genetic screening approaches

J. Stadager, C. Bernardini, L. Hartmann, H. May, J. Wiepcke, M. Kuban, Z. Najafova, S. A. Johnsen, S. Legewie, F. R. Traube, J. Jude, P. Rathert

CRISPRgate improves loss-of-function screening by combining CRISPRko and CRISPRi to enhance gene repression and reduce noise in genetic studies.

bioRxiv · May 14, 2024Biochemistry

SPOP targets the immune transcription factor IRF1 for proteasomal degradation

M. Vunjak, I. Schwartz, A. Cantoran-Garcia, M. Mastrovito, M. Hinterndorfer, M. de Almeida, V. Budroni, J. Wang, K. Froussios, J. Jude, T. Decker, J. Zuber, G. A. Versteeg

This study identifies SPOP as an E3 ligase that targets IRF1 for proteasomal degradation, highlighting its role in regulating IRF1 levels to balance immune response and tumor suppression.

bioRxiv · Oct 10, 2022Cell Biology

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts

P. van der Lelij, S. Lieb, J. Jude, G. Wutz, C. P. Santos, K. Falkenberg, A. Schlattl, J. Ban, R. Schwentner, T. Hoffmann, H. Kovar, F. X. Real, T. Waldman, M. Pearson, N. Kraut, , M. P. Petronczki

The paper identifies a synthetic lethal relationship between STAG1 and STAG2 in cancers, showing STAG1 inactivation selectively targets STAG2-mutated cancer cells.

bioRxiv · Jun 25, 2017Cancer Biology

J. Jude · henhao