Author

M. Petljak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

E. N. Bergstrom· 2 shared A. Dananberg· 1 shared J. Maciejowski· 1 shared J.-C. Luebeck· 1 shared K. Chu· 1 shared L. Alexandrov· 1 shared L. B. Alexandrov· 1 shared M. R. Stratton· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

E. N. Bergstrom

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Author profile →

2 papers

Recent·Most cited

Comprehensive analysis of clustered mutations in cancer reveals recurrent APOBEC3 mutagenesis of ecDNA

E. N. Bergstrom, J.-C. Luebeck, M. Petljak, V. Bafna, P. S. Mischel, R. Harris, L. B. Alexandrov

The paper analyzes clustered mutations in 2,583 cancer genomes, identifying APOBEC3-driven mutagenesis on ecDNA as a significant contributor to cancer evolution.

bioRxiv · May 27, 2021Cancer Biology

The APOBEC3A deaminase drives episodic mutagenesis in cancer cells

M. Petljak, K. Chu, A. Dananberg, E. N. Bergstrom, P. von Morgen, L. Alexandrov, M. R. Stratton, J. Maciejowski

This study shows that APOBEC3A drives episodic mutagenesis in cancer cells by reducing clustered mutations and identifying key enzymes involved in mutation generation.

bioRxiv · Feb 14, 2021 · PreprintCancer Biology