Author

M. Poirot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Websdale· 1 shared D. Luetjohann· 1 shared G. Cioccoloni· 1 shared H. Roberg-Larsen· 1 shared J. L. Thorne· 1 shared L. Pucheu· 1 shared M. A. Zulyniak· 1 shared M. Xu· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Websdale

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2 papers

Recent·Most cited

27-hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor

S. Ayadi, S. Friedrichs, R. Soules, L. Pucheu, D. Luetjohann, S. Silvente-Poirot, M. Poirot, P. de Medina

The paper shows that CYP27A1 converts OCDO into 27H-OCDO, which inhibits breast cancer cell proliferation, switching its activity from pro-tumor to anti-tumor.

bioRxiv · Oct 10, 2023 · PreprintBiochemistry

Pharmacologic and genetic inhibition of cholesterol esterification reduces tumour burden: a pan-cancer systematic review and meta-analysis of preclinical models

A. Websdale, Y. Kiew, P. Chalmers, X. Chen, G. Cioccoloni, T. A. Hughes, X. Luo, R. Mwarazi, M. Poirot, H. Roberg-Larsen, R. Wu, M. Xu, M. A. Zulyniak, J. L. Thorne

This paper reviews preclinical studies showing that inhibiting cholesterol esterification reduces tumour burden across cancers, with SOAT inhibitors like avasimibe showing promise.

bioRxiv · Jun 12, 2021Cancer Biology