Author

G. Cioccoloni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Assay:clinical cohort / trial· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Websdale· 2 shared H. Roberg-Larsen· 2 shared J. L. Thorne· 2 shared T. A. Hughes· 2 shared A. Rose· 1 shared B. Kim· 1 shared B. Williams· 1 shared C. Soteriou· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. Websdale

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2 papers

Recent·Most cited

Pharmacologic and genetic inhibition of cholesterol esterification reduces tumour burden: a pan-cancer systematic review and meta-analysis of preclinical models

A. Websdale, Y. Kiew, P. Chalmers, X. Chen, G. Cioccoloni, T. A. Hughes, X. Luo, R. Mwarazi, M. Poirot, H. Roberg-Larsen, R. Wu, M. Xu, M. A. Zulyniak, J. L. Thorne

This paper reviews preclinical studies showing that inhibiting cholesterol esterification reduces tumour burden across cancers, with SOAT inhibitors like avasimibe showing promise.

bioRxiv · Jun 12, 2021Cancer Biology

Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer

S. A. Hutchinson, A. Websdale, P. Lianto, G. Cioccoloni, H. Roberg-Larsen, B. Kim, A. Rose, C. Soteriou, L. M. Wastall, B. Williams, M. Henn, J. J. Chen, L. Ma, J. B. Moore, E. R. Nelson, , J. L. Thorne

This study identifies LXRalpha as a driver of chemoresistance in TNBC through its regulation of P-glycoprotein, linking cholesterol metabolism to chemotherapy failure.

bioRxiv · Aug 4, 2020Cancer Biology