Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis, and Poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets
C. N. Mavian, A. S. Ramirez-Mata, J. J. Dollar, D. J. Nolan, K. White, S. N. Rich, B. Rife Magalis, M. N. Cash, S. Marini, M. Prosperi, D. Moraga Amador, A. Riva, K. C. Williams, M. Salemi
This study analyzes transcriptomic data from SIV-infected macaques to identify altered metabolic pathways and PARPs as potential therapeutic targets in HIV-associated neurodegeneration.
bioRxiv · May 21, 2020Pathology