Author

K. C. Williams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1

Frequent Co-Authors

B. Rife Magalis· 2 shared M. Salemi· 2 shared A. Riva· 1 shared A. S. Ramirez-Mata· 1 shared A. Schuetz· 1 shared C. Loo· 1 shared C. N. Mavian· 1 shared C. St. Laurent· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPathology

B. Rife Magalis

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Author profile →

3 papers

Recent·Most cited

A Versatile Soluble Siglec Scaffold for Sensitive and Quantitative Detection of Glycan Ligands

E. Rodrigues, J. Jung, H. Park, C. Loo, S. Soukhtehzari, E. N. Kitova, F. Mozaneh, G. Daskhan, V. Aghanya, S. Sarkar, L. Streith, C. St. Laurent, J.-P. Julien, L. C. West, K. C. Williams, , M. S. Macauley

This paper introduces a versatile Siglec-Fc scaffold for detecting glycan ligands, revealing new patterns on healthy and cancerous cells and clarifying ligand specificities, including for CD33.

bioRxiv · Jul 28, 2020Biochemistry

Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis, and Poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets

C. N. Mavian, A. S. Ramirez-Mata, J. J. Dollar, D. J. Nolan, K. White, S. N. Rich, B. Rife Magalis, M. N. Cash, S. Marini, M. Prosperi, D. Moraga Amador, A. Riva, K. C. Williams, M. Salemi

This study analyzes transcriptomic data from SIV-infected macaques to identify altered metabolic pathways and PARPs as potential therapeutic targets in HIV-associated neurodegeneration.

bioRxiv · May 21, 2020Pathology

Monocyte Infection Dynamics Shape HIV-1 Phyloanatomy in the Peripheral Blood

B. Rife Magalis, S. L. Strickland, S. D. Shank, P. Autissier, A. Schuetz, P. Sithinamsuwam, S. Lerdlum, J. L. K. Fletcher, M. de Souza, J. Ananworanich, V. Valcour, K. C. Williams, S. L. Kosakovsky Pond, S. Ratto Kim, M. Salemi, SEARCH007

This study shows that HIV-1 evolves differently in monocytes compared to T cells, suggesting monocytes may be a significant viral reservoir.

bioRxiv · Dec 12, 2018 · PreprintEvolutionary Biology