Interactomic analysis reveals a new homeostatic role for the HIV restriction factor TRIM5α in mitophagy
B. Saha, M. R. Salemi, G. L. Williams, M. L. Paffett, B. Phinney, M. A. Mandell
The paper identifies a novel role for TRIM5α in mitophagy, showing it regulates mitochondrial quality control and prevents cell death under mitochondrial stress.
bioRxiv · Aug 20, 2021Cell Biology