PERK-ATAD3A interaction protects mitochondrial proteins synthesis during ER stress
D. T. Hughes, K. K. Brar, J. Morris, K. Subramanian, S. Krishna, F. Gao, L.-S. Rieder, J. L. Freeman, H. L. Smith, R. Jukes-Jones, J. Nunnari, J. Prudent, A. J. Butcher, G. R. Mallucci
The paper identifies ATAD3A as a PERK interactor that modulates PERK-eIF2 signaling during ER stress, allowing selective translation of mitochondrial proteins.
bioRxiv · Jul 24, 2022 · PreprintCell Biology