Author

M. Rachid

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

C. Ansaldi· 2 shared E. Bestion· 2 shared E. Raymond· 2 shared G. Roth· 2 shared P. Halfon· 2 shared S. MEZOUAR· 2 shared T. Decaens· 2 shared A. Hamai· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. Ansaldi

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeting PPT1 with ezurpimtrostat sensitives liver tumor to immunotherapy by switching cold into hot microenvironments

E. Bestion, M. Rachid, A. Tijeras-Raballand, G. Roth, T. Decaens, C. Ansaldi, S. MEZOUAR, E. Raymond, P. Halfon

This paper shows that inhibiting PPT1 with ezurpimtrostat enhances anti-PD-1 immunotherapy in liver cancer by converting cold to hot tumors.

bioRxiv · Jan 18, 2023 · PreprintCancer Biology

GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions

S. BRUN, E. Raymond, F. Bassissi, Z. M. Jilkova, S. Mezouar, M. Rachid, M. Novello, J. Tracz, A. Hamai, G. Lalmanach, L. Vanderlynden, E. Bestion, R. Legouffe, J. Stauber, T. Schubert, , P. Halfon

This paper evaluates GNS561, a PPT1 inhibitor, showing its efficacy against HCC by modulating lysosomal functions and inducing cell death in vitro and in vivo.

bioRxiv · Sep 30, 2020Cancer Biology