Author

F. Bassissi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

E. Bestion· 2 shared P. Halfon· 2 shared S. Brun· 2 shared S. Mezouar· 2 shared T. Decaens· 2 shared A. Hamai· 1 shared C. Ansaldi· 1 shared C. Caron de Fromentel· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

E. Bestion

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Author profile →

2 papers

Recent·Most cited

GNS561, a new autophagy inhibitor active against cancer stem cells in hepatocellular carcinoma and hepatic metastasis from colorectal cancer

S. Brun, J.-M. Pascussi, E. P. Gifu, E. Bestion, Z. Macek-Jilkova, G. Wang, F. Bassissi, S. Mezouar, J. Courcamberck, P. Merle, T. Decaens, J. Pannequin, P. Halfon, C. Caron de Fromentel

This study shows that GNS561, an autophagy inhibitor, effectively targets both cancer stem cells and bulk tumor cells in hepatocellular carcinoma and colorectal cancer metastasis.

bioRxiv · Dec 21, 2020Cancer Biology

GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions

S. BRUN, E. Raymond, F. Bassissi, Z. M. Jilkova, S. Mezouar, M. Rachid, M. Novello, J. Tracz, A. Hamai, G. Lalmanach, L. Vanderlynden, E. Bestion, R. Legouffe, J. Stauber, T. Schubert, , P. Halfon

This paper evaluates GNS561, a PPT1 inhibitor, showing its efficacy against HCC by modulating lysosomal functions and inducing cell death in vitro and in vivo.

bioRxiv · Sep 30, 2020Cancer Biology