Author

M. Robson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Cancer Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

E. Kokalaki· 2 shared I. Gannon· 2 shared J. Sillibourne· 2 shared M. Pule· 2 shared S. Srivastava· 2 shared S. Thomas· 2 shared T. Grothier· 2 shared A. Bulek· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

E. Kokalaki

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Exploration of T-cell immune responses by expression of a dominant-negative SHP1 and SHP2

J. Taylor, A. Bulek, I. Gannon, M. Robson, E. Kokalaki, T. Grothier, C. McKenzie, M. El-Kholy, M. Stavrou, C. Traynor-White, W. C. Lim, P. Panagiotou, S. Srivastava, V. Baldan, J. Sillibourne, , S. Thomas

This study investigates the role of SHP1 and SHP2 in T-cell immunosuppression by expressing truncated variants and shows that dSHP2 can alleviate PD1-mediated suppression in CAR T cells.

bioRxiv · Apr 26, 2023Immunology

Enhancing CAR T cell therapy using Fab-Based Constitutively Heterodimeric Cytokine Receptors

M. Righi, I. Gannon, M. Robson, S. Srivastava, E. Kokalaki, T. Grothier, F. Nannini, C. Allen, B. Yuchen, J. Sillibourne, S. P. Cordoba, S. Thomas, M. Pule

This paper introduces a dimerization domain from IgG1 antibodies to create engineered cytokine receptors that mimic natural heterodimerization, enhancing CAR T cell therapy efficacy.

bioRxiv · Apr 24, 2023Immunology

Water-Only Look-Locker Inversion recovery (WOLLI) T1 mapping

L. D. Garrison, C. Levick, M. Pavlides, T. Marjot, F. Mozes, L. Hodson, S. Neubauer, M. Robson, C. T. Rodgers

This paper introduces WOLLI, a T1 mapping technique that reduces fat interference, and compares it to ShMOLLI and spectroscopy in simulations, phantoms, and liver scans.

bioRxiv · Jan 28, 2022 · PreprintBiophysics

Enhancer hijacking determines intra- and extrachromosomal circular MYCN amplicon architecture in neuroblastoma

K. Helmsauer, M. Valieva, S. Ali, R. Chamorro Gonzalez, R. Schoepflin, C. Roeefzaad, Y. Bei, H. Dorado Garcia, E. Rodriguez-Fos, M. Puiggros, V. Heinrich, M. Robson, K. Kasack, K. Haase, L. P. Kuschel, , R. P. Koche

The paper identifies two distinct MYCN amplicon structures in neuroblastoma, showing how enhancer hijacking compensates for loss of local regulatory elements.

bioRxiv · Dec 20, 2019Cancer Biology

Range-wide variation in local adaptation and phenotypic plasticity of fitness-related traits in Fagus sylvatica and their implications under climate change

H. Garate-Escamilla, A. Hampe, N. Vizcaino-Palomar, M. Robson, M. Benito Garzon

The paper quantifies local adaptation and phenotypic plasticity of growth and survival traits in Fagus sylvatica across its range and estimates their contribution to species distribution under climate change.

bioRxiv · Jan 7, 2019Ecology