Author

M. S. Kay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Biochemistry· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:rat· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. R. Smith· 2 shared J. N. Francis· 2 shared A. Billet· 1 shared A. E. Siglin· 1 shared A. Gonzalez· 1 shared A. Meola· 1 shared A. P. West· 1 shared A.-C. Vanbaelen· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. R. Smith

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A synthetic delivery vector for mucosal vaccination

A. Billet, J. Hadjerci, T. Tran, P. Kessler, J. Ulmer, G. Mourier, M. Ghazarian, A. Gonzalez, R. Thai, P. Urquia, A.-C. Vanbaelen, A. Meola, I. Fernandez, S. Deville-Foillard, E. MacDonald, , L. Johannes

This paper develops a synthetic delivery vector for mucosal vaccination that induces mucosal immunity and CD8+ T cell responses in mice.

Biomaterials · Nov 1, 2023Peer-reviewedBiochemistry

Prevention and Treatment of SHIVAD8 Infection in Rhesus Macaques by a Potent D-peptide HIV Entry Inhibitor

Y. Nishimura, J. N. Francis, O. Donau, E. Jesteadt, R. Sadjadpour, A. R. Smith, M. S. Seaman, B. D. Welch, M. A. Martin, M. S. Kay

This study demonstrates that CPT31, a D-peptide HIV entry inhibitor, prevents SHIV infection in rhesus macaques and reduces viral load in chronically infected animals.

Proceedings of the National Academy of Sciences · Aug 20, 2020Peer-reviewedMicrobiology

Electron tomography visualization of HIV-1 fusion with target cells using fusion inhibitors to trap the pre-hairpin intermediate

M. S. Ladinsky, P. N. P. Gnanapragasam, Z. Yang, A. P. West, M. S. Kay, P. J. Bjorkman

The paper uses fusion inhibitors to trap HIV-1 in a pre-hairpin intermediate state and visualizes it via electron tomography, revealing the structure of Env-mediated fusion.

bioRxiv · Apr 29, 2020Cell Biology

Conflicts with diarrheal pathogens trigger rapid evolution of an intestinal signaling axis

C. M. Carey, S. E. Apple, Z. A. Hilbert, M. S. Kay, N. C. Elde

The paper investigates how diarrheal pathogens drive evolutionary changes in the GC-C receptor and its ligand in mammals, showing evidence of positive selection and coevolution.

bioRxiv · Mar 29, 2020Evolutionary Biology

Characterization of resistance to a potent D-peptide HIV entry inhibitor

A. R. Smith, M. T. Weinstock, A. E. Siglin, F. G. Whitby, J. N. Francis, C. P. Hill, D. M. Eckert, M. J. Root, M. S. Kay

This study identifies mutations conferring resistance to the D-peptide HIV inhibitor PIE12-trimer and shows they reduce inhibitor affinity but also impair viral fitness.

bioRxiv · Aug 28, 2019Microbiology