Y. Nishimura

Characterization of carotenoid-producing Muricauda sp. strains isolated from the reef-building coral Galaxea fascicularis and subtropical seawater

This study characterizes two Muricauda sp. strains isolated from coral and seawater, showing they produce carotenoids that may protect zooxanthellae from environmental stress.

Cell surface architecture of the cultivated DPANN archaeon Nanobdella aerobiophila

This study characterizes the cell surface structures and symbiotic interactions of the DPANN archaeon Nanobdella aerobiophila using electron microscopy, transcriptomics, and genomics.

Distinct groups of RNA viruses associated with thermoacidophilic bacteria

The paper identifies two new groups of RNA viruses associated with thermoacidophilic bacteria in acidic hot springs and other environments.

Facioscapulohumeral muscular dystrophy is associated with altered myoblast proteome dynamics

This study uses proteomic analysis to show that FSHD myoblasts have altered mitochondrial protein abundance and turnover rates compared to unaffected siblings.

Distribution and survival strategies of diazotrophs in the Arctic Ocean revealed by global-scale metagenomic analysis

This study identifies diazotrophs in the Arctic Ocean through metagenomic analysis, revealing their distribution, survival strategies, and ecological roles in nitrogen fixation.

CD4-binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wildtype animals

This study shows that CD4bs immunogens can elicit potent, broad anti-HIV-1 neutralizing antibodies in transgenic and wildtype animals.

Proton-pumping rhodopsins in marine diatoms

This study identifies diatom rhodopsin as a light-driven proton pump localized to plastid membranes and suggests it contributes to a CO2-concentrating mechanism in diatoms.

Ubiquitin E3 ligases Atrogin-1 and MuRF1 protein contents are differentially regulated in the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 myotubes

This study shows that Atrogin-1 and MuRF1 protein levels are differentially regulated by the mTOR-S6K1 pathway in C2C12 myotubes, with Atrogin-1 responding to rapamycin inhibition.

Prevalence of viral frequency-dependent infection in coastal marine prokaryotes revealed using monthly time series virome analysis

The paper analyzes monthly virome and 16S rRNA data from Osaka Bay to show frequency-dependent viral infection in marine prokaryotes, regardless of host growth strategy.

The OceanDNA MAG catalog contains over 50,000 prokaryotic genomes originated from various marine environments

The paper presents a catalog of 52,325 prokaryotic genomes from marine environments, expanding known phylogenetic diversity by 34.2% and including 6,256 novel species.

Crosstalk between myosin II and formin functions in the regulation of force generation and actomyosin dynamics in stress fibers

The paper measures traction forces and actomyosin dynamics in stress fibers, revealing that actin turnover and traction forces depend on both myosin II and formin activities.

The Formin Inhibitor, SMIFH2, Inhibits Members of the Myosin Superfamily

The paper shows SMIFH2 inhibits myosin ATPase activity and actin filament translocation, affecting myosin 2A, myosin 10, and other non-muscle myosins, suggesting caution in using SMIFH2 to infer formin function.

Prevention and Treatment of SHIVAD8 Infection in Rhesus Macaques by a Potent D-peptide HIV Entry Inhibitor

This study demonstrates that CPT31, a D-peptide HIV entry inhibitor, prevents SHIV infection in rhesus macaques and reduces viral load in chronically infected animals.

A Broadly Neutralizing Macaque Monoclonal Antibody Against the HIV-1 V3-Glycan Patch

This paper reports a broadly neutralizing monoclonal antibody from a macaque infected with SHIVAD8 that targets the V3-glycan patch of HIV-1 Env, showing neutralizing activity and protective efficacy in vivo.

Non-invasive brain-spine interface: continuous brain control of trans-spinal magnetic stimulation using EEG

This paper presents a non-invasive brain-spine interface that uses EEG to control trans-spinal magnetic stimulation for leg neurorehabilitation, showing efficient artifact removal and user comfort.

Hydroxide Ion Carrier for Proton Pump in Bacteriorhodopsin: Primary Proton Transfer

This study uses quantum-mechanical simulations to reveal a hydroxide ion mechanism for primary proton transfer in bacteriorhodopsin, showing the role of specific internal water molecules in the process.

Genome-resolved viral and cellular metagenomes revealed potential key virus-host interactions in a deep freshwater lake

This study analyzes metagenomic data from a freshwater lake to identify viral-host interactions and diversity patterns in viral and bacterial communities.

The cytoskeleton as a smart composite material: A unified pathway linking microtubules, myosin-II filaments and integrin adhesions

This paper identifies KANK proteins as mediators linking microtubules to integrin adhesions, showing how microtubule disconnection triggers myosin-IIA filament assembly and remodeling of focal adhesions and podosomes.