Author

M. Salvucci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 7

Signature Assays, Organisms & Methods

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Organism:human· 7 Approach:statistical model· 5 Assay:imaging· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. H. M. Prehn· 5 shared D. B. Longley· 4 shared E. McDonough· 3 shared F. Ginty· 3 shared S. Cho· 3 shared S. Van Schaeybroeck· 3 shared A. Santamaria-Pang· 2 shared A. Sood· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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5 shared papersCancer Biology

J. H. M. Prehn

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7 papers

Recent·Most cited

Spatial Effects of Infiltrating T cells on Neighbouring Cancer Cells and Prognosis in Stage III CRC patients

M. Azimi, S. Cho, E. Bozkurt, E. McDonough, B. Kisakol, A. Matveeva, M. Salvucci, H. Dussmann, C. Firat, N. Urganci, J. Shia, S. McDade, D. B. Longley, F. Ginty, J. H. M. Prehn

The paper investigates the spatial relationship between T cells and cancer cells in stage III CRC patients, finding that closer proximity of T cells to cancer cells is associated with better disease-free survival.

bioRxiv · Jan 30, 2024Cancer Biology

Identification of inter- and intra-tumoral molecular phenotypes steering temozolomide resistance in patient-derived glioblastoma cells.

F. Fabro, T. V. Kers, K. J. Feller, C. Beerens, I. Ntafoulis, A. Idbaih, M. Verrault, K. Connor, A. Biswas, M. Salvucci, J. H. M. Prehn, A. T. Byrne, A. C. O'Farrell, D. Lambrechts, G. Dilcan, , S. Leenstra

This study identifies two molecular phenotypes, ADA and N-ADA, associated with temozolomide resistance in glioblastoma cells through bulk and single-cell RNA sequencing.

bioRxiv · Aug 11, 2023Cancer Biology

Identification and characterization of four bacteriome- and mycobiome-derived subtypes in tumour and adjacent mucosa tissue of colorectal cancer patients

M. Salvucci, L. Poynter, R. Minerzami, S. Carberry, R. O'Byrne, J. Alexander, D. Lambrechts, K. Veselkov, J. Kinross, J. H. M. Prehn

This paper identifies four microbial subtypes in colorectal cancer tumours and adjacent mucosa, linking them to clinical and molecular features and demonstrating prognostic value.

bioRxiv · Sep 27, 2022 · PreprintCancer Biology

Patients with mesenchymal tumours and high Fusobacteriales prevalence have worse prognosis in colorectal cancer (CRC)

M. Salvucci, N. T. Crawford, K. Stott, S. Bullman, D. B. Longley, J. H. Prehn

bioRxiv · May 17, 2021Cancer Biology

An atlas of inter- and intra-tumor heterogeneityof apoptosis competency in colorectal cancertissue at single cell resolution

A. U. Lindner, M. Salvucci, E. MCDonough, S. Cho, X. Stachtea, E. P. O'Connell, A. D. Corwin, A. Santamaria-Pang, S. Carberry, M. Fichtner, S. Van Schaeybroeck, P. Laurent-Puig, J. P. Burke, D. McNamara, M. Lawler, , J. H. Prehn

The paper generates an atlas of apoptosis susceptibility heterogeneity in colorectal cancer using single-cell analysis and ODE modeling, identifying intrinsic cellular differences in apoptosis competency.

bioRxiv · Mar 19, 2021Cancer Biology

Stratification Of Chemotherapy-Treated Stage III Colorectal Cancer Patients Using Multiplexed Imaging And Single Cell Analysis Of T Cell Populations

X. Stachtea, M. B. Loughrey, M. Salvucci, A. Lindner, S. Cho, E. McDonough, A. Sood, J. Graf, A. Santamaria-Pang, A. Corwin, P. Laurent-Puig, S. Dasgupta, S. Van Schaeybroeck, M. Lawler, J. H. M. Prehn, , D. B. Longley

This study uses multiplexed imaging and single-cell analysis to classify immune cells in stage III colorectal cancer patients, finding that multi-marker Treg classification better predicts survival than single markers.

bioRxiv · Feb 24, 2021Cancer Biology

TRAIL signalling promotes entosis in colorectal cancer

E. Bozkurt, H. Dussmann, M. Salvucci, B. Cavanagh, S. Van Schaeybroeck, D. B. Longley, S. J. Martin, J. H. M. Prehn

This study identifies TRAIL as a promoter of entosis in colorectal cancer cells and links CICs to poor patient prognosis.

bioRxiv · Sep 29, 2020Cancer Biology