Author

C. Firat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Shia· 3 shared J. Garcia-Aguilar· 2 shared A. C. Perez· 1 shared A. Luthra· 1 shared A. Mahmoud· 1 shared A. Matveeva· 1 shared A. Moorman· 1 shared A. Saxena· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

J. Shia

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Author profile →

3 papers

Recent·Most cited

Spatial Effects of Infiltrating T cells on Neighbouring Cancer Cells and Prognosis in Stage III CRC patients

M. Azimi, S. Cho, E. Bozkurt, E. McDonough, B. Kisakol, A. Matveeva, M. Salvucci, H. Dussmann, C. Firat, N. Urganci, J. Shia, S. McDade, D. B. Longley, F. Ginty, J. H. M. Prehn

The paper investigates the spatial relationship between T cells and cancer cells in stage III CRC patients, finding that closer proximity of T cells to cancer cells is associated with better disease-free survival.

bioRxiv · Jan 30, 2024Cancer Biology

Progressive plasticity during colorectal cancer metastasis

A. Moorman, F. Cambuli, E. Benitez, Q. Jiang, Y. Xie, A. Mahmoud, M. Lumish, S. Hartner, S. Balkaran, J. Bermeo, S. Asawa, C. Firat, A. Saxena, A. Luthra, V. Sgambati, , K. Ganesh

This study identifies progressive plasticity in colorectal cancer metastases, showing reprogramming into fetal progenitor states and divergent differentiation, linked to poor survival.

bioRxiv · Aug 18, 2023Cancer Biology

A new immunocompetent rectal cancer model to study radiation therapy

J. K. Kim, C. Wu, M. Del Latto, Y. Gao, S.-H. Choi, M. Kierstead, C.-E. G. Sauve, C. Firat, A. C. Perez, J. Sillanpaa, C.-T. Chen, K. E. Lawrence, P. B. Paty, F. M. Barriga, J. Shia, , J. J. Smith

This paper introduces a mouse model of rectal cancer that mimics human tumor progression and radiation response for preclinical studies.

bioRxiv · Feb 7, 2022 · PreprintCancer Biology