Author

M. Schenk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Johnson· 1 shared A. Klopstein· 1 shared A.-K. König· 1 shared B. Engelhardt· 1 shared B. J. Caldarone· 1 shared C. A. Lemere· 1 shared C. Conrad· 1 shared C. Eckert· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. Johnson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Brain endothelial antigen presentation detains CD8+ T cells at the blood-brain barrier leading to its breakdown

S. Aydin, J. Pareja, V. M. Schallenberg, A. Klopstein, T. Gruber, N. Page, E. Kaba, U. Deutsch, A. Johnson, M. Schenk, D. Merkler, B. Engelhardt

The paper shows that brain endothelial antigen presentation inhibits CD8+ T-cell movement and causes BBB breakdown in MS.

bioRxiv · Oct 12, 2021 · PreprintImmunology

Deep molecular characterization linked to drug response profiling of pancreatic ductal adenocarcinoma using patient-derived organoids.

S. Le Blanc, N. Ishaque, J. Jabs, T. Bauer, S. Schuth, Q. Hu, O. Debnath, F. W. Ten, C.-S. Leonhardt, A.-K. König, M. Bieg, C. Eckert, M. M. Gaida, M. Volkmar, D. Hübschmann, , O. Strobel

This study uses patient-derived PDAC organoids to integrate genomic, transcriptomic, and drug response data, identifying novel biomarkers and resistance mechanisms for personalized treatment.

bioRxiv · Aug 26, 2021 · PreprintCancer Biology

Ultrasound-mediated blood-brain barrier disruption improves anti-pyroglutamate3 Aβ antibody efficacy and enhances phagocyte infiltration into brain in aged Alzheimer's disease-like mice

Q. Shi, T. Sun, Y. Zhang, C. Power, C. Hoesch, S. Antonelli, M. K. Schroeder, B. J. Caldarone, N. Taudte, M. Schenk, S. Schilling, N. McDannold, C. A. Lemere

This paper shows that combining ultrasound with an antibody improves Aβ removal and memory in Alzheimer's mice without causing brain bleeding.

bioRxiv · Jan 15, 2021 · PreprintBioengineering