M. Stumpe

Targeted proteomics addresses selectivity and complexity of protein degradation by autophagy

This study uses targeted proteomics to analyze protein degradation patterns during autophagy, revealing differential responses of selective autophagy receptors to various stimuli.

The pyruvate dehydrogenase complex regulates mitophagic selectivity and matrix protein phosphorylation

The paper identifies a novel role of the pyruvate dehydrogenase complex in regulating mitophagic selectivity independently of its enzymatic activity.

Fibrin, Bone Marrow Cells and macrophages interactively modulate cardiomyoblast fate.

This study shows that fibrin and bone marrow cells reduce cardiac damage and improve function after myocardial infarction by modulating macrophage behavior and promoting cardiomyoblast proliferation.

Dedicated chaperones coordinate co-translational regulation of ribosomal protein production with ribosome assembly to preserve proteostasis

The paper shows that dedicated chaperones prevent degradation of RPL3 and RPL4 mRNAs in yeast by coordinating ribosomal protein production with ribosome assembly.

Dual control of MAPK activities by AP2C1 and MKP1 MAPK phosphatases regulates defence responses in Arabidopsis

This study shows that AP2C1 and MKP1 phosphatases regulate MAPK activity in Arabidopsis, preventing autoimmune-like stress responses by controlling MPK6.

Collective regulation of metabolism, development and longevity through a socially exchanged fluid

The paper uses proteomics to analyze trophallactic fluid in carpenter ants, showing how different colony stages prioritize distinct protein functions related to metabolism, development, and longevity.