Author

M. T. Ciudad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

S. Lamorte· 2 shared T. L. McGaha· 2 shared A. Fomina· 1 shared A. P. McGuigan· 1 shared C. Yu· 1 shared I. L. Co· 1 shared J. L. Cadavid· 1 shared K. R. Campbell· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

S. Lamorte

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Dabrafenib alters MDSC differentiation and function by activation of GCN2

M. T. Ciudad, R. Quevedo, S. Lamorte, R. Jin, N. Nzirorera, M. Koritzinsky, T. L. McGaha

This study shows that dabrafenib inhibits PMN-MDSC differentiation via GCN2 activation, altering their function and reducing their suppressive activity in tumors.

bioRxiv · Aug 9, 2023Immunology

An Engineered 3D Co-culture Model of Primary Macrophages and Patient-Derived Tumour Cells to Explore Cellular Responses in the Graded Hypoxic Microenvironment of Pancreatic Cancer

I. L. Co, C. Yu, S. Lamorte, M. T. Ciudad, N. Landon-Brace, J. L. Cadavid, Z. Xia, A. Fomina, M. Nurse, T. L. McGaha, K. R. Campbell, A. P. McGuigan

This paper develops a 3D co-culture model of macrophages and PDAC organoids to study hypoxia-driven cellular interactions and their impact on chemoresistance and immune responses.

bioRxiv · Jul 13, 2023 · PreprintBioengineering