Author

M. Nurse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. P. McGuigan· 2 shared T. L. McGaha· 2 shared A. Fomina· 1 shared C. A. Simmons· 1 shared C. H. Arrowsmith· 1 shared C. Yu· 1 shared E. D'Arcangelo· 1 shared F. Sun· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

A. P. McGuigan

Mutual co-authors in cluster

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2 papers

Recent·Most cited

EHMT2/G9a-Inhibition Reprograms Cancer-Associated Fibroblasts (CAFs) to a More Differentiated, Less Proliferative and Invasive State

N. C. Wu, R. Quevedo, M. Nurse, K. Hezaveh, H. Liu, F. Sun, J. Muffat, Y. Sun, C. A. Simmons, T. L. McGaha, P. Prinos, C. H. Arrowsmith, L. Ailles, E. D'Arcangelo, A. P. McGuigan

This study identifies EHMT2 as a key regulator of CAF hyperproliferation and pro-invasive behavior, showing its inhibition reprograms CAFs to a less aggressive state.

bioRxiv · Jul 17, 2023 · PreprintCancer Biology

An Engineered 3D Co-culture Model of Primary Macrophages and Patient-Derived Tumour Cells to Explore Cellular Responses in the Graded Hypoxic Microenvironment of Pancreatic Cancer

I. L. Co, C. Yu, S. Lamorte, M. T. Ciudad, N. Landon-Brace, J. L. Cadavid, Z. Xia, A. Fomina, M. Nurse, T. L. McGaha, K. R. Campbell, A. P. McGuigan

This paper develops a 3D co-culture model of macrophages and PDAC organoids to study hypoxia-driven cellular interactions and their impact on chemoresistance and immune responses.

bioRxiv · Jul 13, 2023 · PreprintBioengineering