Author

M. Volcic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

F. Kirchhoff· 4 shared C. Prelli Bozzo· 3 shared F. Zech· 3 shared R. Nchioua· 3 shared A. Kleger· 2 shared C. Pastorio· 2 shared J. Krueger· 2 shared K. M. J. Sparrer· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

F. Kirchhoff

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Attenuated replication and damaging effects of SARS-CoV-2 Omicron in an intestinal epithelial barrier model

M. Volcic, R. Nchioua, C. Pastorio, F. Zech, C. Read, P. Walther, F. Kirchhoff

This study compares the effects of SARS-CoV-2 early strains and Omicron variants on intestinal barrier function using a human gut epithelial model, finding Omicron causes less damage.

bioRxiv · Feb 28, 2024Immunology

Traitor-virus-guided discovery of novel antiviral factors

C. Prelli Bozzo, A. Laliberte, A. De Luna, C. Pastorio, K. Regensburger, S. Krebs, A. Graf, H. Blum, M. Volcic, K. M. Sparrer, F. Kirchhoff

This study uses HIV-guided CRISPR to identify antiviral factors by analyzing sgRNA enrichment during viral replication.

bioRxiv · Nov 3, 2023 · PreprintMicrobiology

Spike mutation T403R allows bat coronavirus RaTG13 to use human ACE2

F. Zech, D. Schniertshauer, C. Jung, A. Herrmann, Q. Xie, R. Nchioua, C. Prelli Bozzo, M. Volcic, L. Koepke, J. Krueger, S. Heller, A. Kleger, T. Jacob, K.-K. Conzelmann, A. Ensser, , F. Kirchhoff

The paper shows that a single amino acid mutation in the Spike protein of bat coronavirus RaTG13 enables it to use human ACE2 for infection.

bioRxiv · May 31, 2021 · PreprintMicrobiology

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition

C. Prelli Bozzo, R. Nchioua, M. Volcic, J. Krueger, S. Heller, C. M. Stuerzel, D. Kmiec, C. Conzelmann, J. A. Mueller, F. Zech, D. Schuetz, L. Koepke, E. Braun, R. Gross, L. Wettstein, , F. Kirchhoff

This study shows that IFITM proteins are required for SARS-CoV-2 infection and can be targeted to inhibit viral entry and replication.

bioRxiv · Aug 18, 2020 · PreprintMicrobiology