Author

Macee C. Owen

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Kory J. LavineiD· 2 shared Alekhya ParvathaneniiD· 1 shared Andrea L. BredemeyeriD· 1 shared Andrew B. JanowskiiD· 1 shared Andrew L. KoenigiD· 1 shared Ashley Hahn· 1 shared Attila Kovacs· 1 shared Avash DasiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

Kory J. LavineORCID

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3 papers

Recent·Most cited

CD14 Blockade Attenuates Arrhythmogenic Cardiomyopathy

Vinay R. Penna, Emily A. Shiel, Waleed Farra, Elisa Nicole Cannon, Maicon Landim-Vieira, Macee C. Owen, Rajiu Venkatesan, Gyu Seong Heo, Avash Das, Yongjian Liu, Mark W. Appleby, David. T. Crowe, Brian. W. Ziegelaar, Garry L. Redlich, Jeffrey E. Saffitz, , Kory J. Lavine

This study shows that blocking CD14 reduces arrhythmogenic cardiomyopathy in mice by decreasing inflammation and fibrosis.

bioRxiv · Oct 7, 2026 · PreprintImmunology

Collateral Immune Cell Signaling Compromises the Efficacy of T-cell Engaging Therapies for Cardiac Fibrosis

Steven Hoseong Yang, Alekhya Parvathaneni, Yun-Ling Pai, Andrew L. Koenig, Farid F. Kadyrov, Macee C. Owen, Junedh Amrute, Andrea L. Bredemeyer, Yu-Sung Hsu, Attila Kovacs, Carla J. Weinheimer, Jessica M. Nigro, Lance Yeh, Thomas Williamson, Blake Jardin, , Kory J. Lavine

This study shows that FAP-targeted BiTE(R) molecules, intended to reduce cardiac fibrosis, instead worsen heart function by triggering harmful immune responses.

bioRxiv · Sep 21, 2026 · PreprintImmunology

Novel murine model of human astrovirus infection reveals a cardiovascular tropism

Macee C. Owen, Yuefang Zhou, Holly M. Dudley, Taylor Feehley, Ashley Hahn, Christine C. Yokoyama, Margaret L. Axelrod, Chieh‐Yu Lin, David Wang, Andrew B. Janowski

This paper develops a novel murine model of human astrovirus infection, revealing a cardiovascular tropism and immune response mechanisms.

Journal of Virology · Apr 30, 2025Peer-reviewedMicrobiology