Transcripts with high distal heritability mediate genetic effects on complex metabolic traits
Anna L. Tyler, J. Matthew Mahoney, Mark P. Keller, Candice N. Baker, Margaret Gaca, Anuj Srivastava, Isabela Gerdes Gyuricza, Madeleine Braun, Nadia A Rosenthal, Alan Attie, Gary A. Churchill, Gregory W. Carter
The paper identifies a composite transcriptome signature with high distal heritability that explains 30% of metabolic trait variation across species.
Nature Communications · Jul 1, 2025Peer-reviewedGenetics