Olga Rosspopoff

The paper identifies the Lipid Oxygen Radical Defense (LORD) pathway and shows it is epigenetically controlled, affecting oxidative stress and ferroptosis.

The paper shows ZNF93, a primate-specific protein, regulates APOBEC3B and influences cancer progression by affecting DNA synthesis and genomic stability.

This study identifies evolutionarily recent transcription factors that influence human cell cycle regulation by affecting gene expression and replication timing.

The paper identifies a noncanonical role for KZFPs in restricting TE-derived regulatory elements to maintain cell-type identity, independent of TRIM28.

The paper shows that a transposable element-derived domain in KRAB zinc-finger proteins enables new transcription factor functions through trimerization and condensate formation.

This study identifies ZNF274's role in anchoring lineage-specific gene clusters within repressive perinucleolar compartments, revealing its impact on chromatin structure and gene regulation.

The paper uses live imaging in zebrafish to show that Tbx6 expression waves, driven by Hes/Her genes, prefigure somite boundaries by arresting in boundary cells that later express Mesp.

The paper identifies a primate-specific retroviral enhancer that integrates the XACT lncRNA into the human pluripotency network through evolutionary adaptation.

The paper investigates the mechanistic differences in XIST regulatory networks between humans and mice, showing that JPX regulates XIST expression through distinct mechanisms in each species.