Mandy Börmel

A dsRNA Virus Converts Early Endosomes into Stable Replication Organelles Through Maturation Arrest and Retrograde Transport

This study reveals how birnaviruses use VP3 to remodel endosomes into replication compartments through PtdIns(3)P-dependent mechanisms, showing conservation and host adaptation across IBDV and IPNV.

The small GTPase Ran defines Nuclear Pore Complex asymmetry

This study shows that the small GTPase Ran controls the asymmetry of nuclear pore complexes by regulating their peripheral configuration in budding yeast and Drosophila.

Cell volume regulates terminal differentiation of cultured human epidermal keratinocytes

This study shows that cell volume, influenced by substrate interactions and osmotic treatments, regulates differentiation of human epidermal keratinocytes independently of substrate topography.