Enhancing autophagy by redox regulation extends lifespan in Drosophila
Claudia Lennicke, Ivana Bjedov, Sebastian Grönke, Katja E. Menger, Andrew M. James, Jorge Iván Castillo-Quan, Lucie A.G. van Leeuwen, Andrea Foley, Marcela Buricova, Jennifer Adcott, Alex Montoya, Holger Kramer, Pavel V. Shliaha, Angela Logan, Filipe Cabreiro, , Helena M. Cochemé
This study shows that enhancing autophagy through redox regulation extends lifespan in Drosophila by highlighting the role of a specific cysteine residue in Atg4a.
bioRxiv · May 10, 2024 · PreprintMolecular Biology