Filipe Cabreiro

This study identifies bacterial enterobactin as a non-canonical neurotransmitter that modulates host behavior and aging via mitochondrial function and redox state.

The paper shows that combining biotin biosynthesis inhibition with metformin reduces Pseudomonas aeruginosa virulence and restores antibiotic sensitivity by targeting metabolic pathways.

This study shows mitochondrial dysfunction accelerates aging by disrupting gut microbiota structure and inducing immune dysregulation and inflammation through metabolic reprogramming.

The paper develops a pangenome framework using a protein language model to link E. coli genetic diversity to host proteostasis by analyzing functional guilds and metabolic interactions.

This study shows that enhancing autophagy through redox regulation extends lifespan in Drosophila by highlighting the role of a specific cysteine residue in Atg4a.

The paper develops a bacterial biosensor system in C. elegans to detect environmental changes in the intestinal tract using an inducer.

The paper introduces a label-free automated method to score nematode survival in high-throughput assays and finds an autophagy-dependent increase in acute stress resistance in early adulthood.