Author

Lucie A.G. van Leeuwen

University Medical Center UtrechtORCID 0009-0001-6901-7789Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Alex MontoyaiD· 1 shared Andrea Foley· 1 shared Andrew M. JamesiD· 1 shared Angela LoganiD· 1 shared Aniek JansseniD· 1 shared Claudia LennickeiD· 1 shared Desiree M C Smakman· 1 shared Filipe CabreiroiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Alex MontoyaORCID

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2 papers

Recent·Most cited

Mapping subcellular H2O2 dynamics reveals tissue specific redox patterns in Drosophila

Lucie A.G. van Leeuwen, Silvia Casanova, Oisharja Rahman, Maura C Hooiveld, Desiree M C Smakman, Jan-Paul Lambooij, Tobias B. Dansen, Aniek Janssen, Hayley J. Sharpe

The paper develops FlyPer, a Drosophila H2O2 biosensor toolkit, to measure subcellular H2O2 dynamics in vivo, revealing tissue-specific redox patterns during development and stress.

bioRxiv · Aug 24, 2026 · PreprintCell Biology

Enhancing autophagy by redox regulation extends lifespan in Drosophila

Claudia Lennicke, Ivana Bjedov, Sebastian Grönke, Katja E. Menger, Andrew M. James, Jorge Iván Castillo-Quan, Lucie A.G. van Leeuwen, Andrea Foley, Marcela Buricova, Jennifer Adcott, Alex Montoya, Holger Kramer, Pavel V. Shliaha, Angela Logan, Filipe Cabreiro, , Helena M. Cochemé

This study shows that enhancing autophagy through redox regulation extends lifespan in Drosophila by highlighting the role of a specific cysteine residue in Atg4a.

bioRxiv · May 10, 2024 · PreprintMolecular Biology