Author

Marco Hagenmüller

Heidelberg University

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Physiology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1

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Alireza SaadatmandiD· 1 shared Almut SchulzeiD· 1 shared Christoph MaackiD· 1 shared Harikrishnareddy Paluvai· 1 shared Jens Tyedmers· 1 shared Johannes BacksiD· 1 shared Joshua Hartmann· 1 shared Lisa SchlickeriD· 1 shared

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1 shared paperPhysiology

Alireza SaadatmandORCID

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1 paper

Recent·Most cited

PhysiologybioRxivPreprintOct 16, 2025

CAMK2-NR4A1 signaling initiates metabolic substrate switching to induce heart failure with reduced ejection fraction

Alireza Saadatmand, Mark E. Pepin, Zihao Chen…·Johannes Backs

The paper identifies CAMK2-NR4A1 signaling as a driver of metabolic substrate switching in heart failure with reduced ejection fraction, linking it to cardiac dysfunction through glucose utilization and lipid depletion.

DOI 10.1101/2025.10.16.682731

mouseimaging

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