Author

Maria Alimova

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Adam P. SkepneriD· 1 shared Alexandra–Chloé VillaniiD· 1 shared Alison LeediD· 1 shared Amy A. Deik· 1 shared Anna GrekaiD· 1 shared Astrid WeinsiD· 1 shared Aviv RegeviD· 1 shared Ayan GhoshaliD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

Adam P. SkepnerORCID

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Author profile →

3 papers

Recent·Most cited

Phenotypic screening converges on CDK9 inhibition as a therapeutic strategy in translocation renal cell carcinoma

Dharma R. Thapa, Riva Deodhar, Adam P. Skepner, Prathyusha Konda, Meng Zhou, Joseph P. Bluck, C. Pichlo, Yantong Cui, Paige Stocker, Prateek Khanna, Jiao Li, Jonathan M. Tsai, Alison Leed, Sandy Gould, Maria Alimova, , Srinivas Raghavan Viswanathan

The paper identifies CDK9 inhibition as a therapeutic strategy for translocation renal cell carcinoma through phenotypic screening and mechanistic analysis.

bioRxiv · Aug 25, 2025 · PreprintCancer Biology

Obesity-instructed TREM2high macrophages identified by comparative analysis of diabetic mouse and human kidney at single cell resolution

Ayshwarya Subramanian, Katherine A. Vernon, Yiming Zhou, Jamie L. Marshall, Maria Alimova, Fan Zhang, Michal Slyper, Julia Waldman, Mónica S. Montesinos, Danielle Ashley Dionne, Lan Nguyễn, Michael S. Cuoco, Dan Dubinsky, Jason Purnell, Keith Heller, , Anna Greka

The paper identifies obesity-related TREM2high macrophages in diabetic mouse and human kidney through single-cell transcriptomics and cross-species comparison.

bioRxiv · May 30, 2021 · PreprintGenomics

HIF-2α drives an intrinsic vulnerability to ferroptosis in clear cell renal cell carcinoma

Yilong Zou, Michael J. Palte, Amy A. Deik, Haoxin Li, John K. Eaton, Wenyu Wang, Yuen-Yi Tseng, Rebecca Deasy, Maria Alimova, Vlado Dančík, Elizaveta S. Leshchiner, Vasanthi S. Viswanathan, Sabina Signoretti, Toni K. Choueiri, Jesse S. Boehm, , Stuart L. Schreiber

This paper identifies a vulnerability in clear-cell renal cell carcinoma cells to ferroptosis induced by GPX4 inhibition, driven by the HIF-2-HILPDA pathway and PUFA-lipid enrichment.

bioRxiv · Aug 9, 2018 · PreprintCancer Biology