Author

Marion Sangiardi

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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Christian LévêqueiD· 4 shared Kévin Debreux· 4 shared MICHAEL J. SEAGARiD· 4 shared Oussama El FariD· 4 shared Jorge Ramírez‐FrancoiD· 3 shared Maya BelghaziiD· 3 shared Sarosh R. IraniiD· 2 shared Claire DebarnotiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Christian LévêqueORCID

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4 papers

Recent·Most cited

Leucine-rich glioma inactivated 1 is a ganglioside-binding protein

Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R. Irani, MICHAEL J. SEAGAR, Jacques Fantini, Oussama El Far

The paper shows LGI1 binds gangliosides and may organize lipid platforms for ion channels, and its loss disrupts these platforms in mice.

bioRxiv · Feb 8, 2026 · PreprintNeuroscience

A hyperglycosylated form of Kv1.2 upregulated in LGI1 knockout mice

Jorge Ramírez‐Franco, Marion Sangiardi, Kévin Debreux, Maya Belghazi, Christian Lévêque, MICHAEL J. SEAGAR, Oussama El Far

The paper identifies a hyperglycosylated and phosphorylated form of Kv1.2 upregulated in Lgi1-/- mice and reports changes in its interactome.

bioRxiv · Oct 29, 2025 · PreprintNeuroscience

Molecular Basis of Kv1 Channel Downregulation and Its Epileptogenic Implications in Lgi1 Knock-out Mice

Jorge Ramírez‐Franco, Kévin Debreux, Marion Sangiardi, Maya Belghazi, Yujin Kim, Suk‐Ho Lee, Christian Lévêque, MICHAEL J. SEAGAR, Oussama El Far

This study investigates Kv1 channel downregulation in LGI1 knock-out mice, showing it occurs in somatodendritic regions and is linked to increased neuronal bursting and changes in the Kv1 interactome.

bioRxiv · Jul 24, 2023 · PreprintNeuroscience

Patient-derived recombinant autoantibodies reveal the subcellular neuroglial distribution and heterogeneous interactome of leucine-rich glioma-inactivated 1

Jorge Ramírez‐Franco, Kévin Debreux, Johanna Extrémet, Yves Maulet, Maya Belghazi, Claude Villard, Marion Sangiardi, Fahamoe Youssouf, Lara El Far, Christian Lévêque, Claire Debarnot, P. Marchot, Sofija Paneva, Dominique Debanne, Michaël Russier, , Oussama El Far

The paper uses patient-derived autoantibodies to study LGI1 localization and interactome in mouse brains, revealing its synaptic distribution and novel protein complexes.

bioRxiv · Mar 29, 2022 · PreprintNeuroscience