Author

Mark N Metri

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Jeehye ParkiD· 2 shared Jhune Rizsan SantosiD· 2 shared Jooyun LeeiD· 2 shared Justin YouiD· 2 shared Katarina Maksimovic· 2 shared Mohieldin YoussefiD· 2 shared Alison MaoiD· 1 shared Anneka Schoeppe· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersNeuroscience

Jeehye ParkORCID

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3 papers

Recent·Most cited

Early MATR3 loss and distinct neurodegenerative molecular signatures precede the onset of neuropathology in motor neurons and Purkinje cells of MATR3 S85C knock-in mouse model of ALS

Katarina Maksimovic, Majji Rambabu, Jhune Rizsan Santos, Cadia Chan, Anneka Zelaya, Jooyun Lee, Michelle Dias, Oxana B. Gluscencova, Mohieldin Youssef, Sandra Kim, Tiara Noronha, Christine Lai, Y. B. Fan, Mark N Metri, Justin You, , Jeehye Park

bioRxiv · Aug 31, 2026 · PreprintNeuroscience

Stochastic Misfolding Drives the Emergence of Distinct α-Synuclein Strains

Raphaella W. L. So, Benedikt Frieg, José D. Camino, Christopher Situ, Mark N Metri, Nicholas R. G. Silver, Le yao Li, Alison Mao, Erica Stuart, G.F. Schroeder, Joel C. Watts

This study shows that stochastic misfolding leads to the formation of distinct α-synuclein strains both in vitro and in vivo, resulting in different disease phenotypes.

Neuron · Feb 27, 2026Peer-reviewedNeuroscience

Knockout of Dectin-1 does not modify disease onset or progression in a MATR3 S85C knock-in mouse model of ALS

Justin You, Katarina Maksimovic, Mark N Metri, Anneka Schoeppe, Karin Chen, Jooyun Lee, Jhune Rizsan Santos, Mohieldin Youssef, Michael W. Salter, Jeehye Park

Heliyon · Sep 1, 2024Peer-reviewedNeuroscience