Targeted detection of endogenous LINE-1 proteins and ORF2p interactions
Mathias Ingemann Nielsen, Justina Clarinda Wolters, Omar G. Rosas Bringas, Hua Liang Jiang, Luciano H. Di Stefano, Mehrnoosh Oghbaie, Samira Hozeifi, Mats J. Nitert, Alienke van Pijkeren, Marieke Smit, Lars ter Morsche, Apostolos Mourtzinos, Vikram Deshpande, Martin S. Taylor, Brian T. Chait, John LaCava
This paper develops targeted mass spectrometry assays to detect and quantify endogenous ORF1p and ORF2p proteins, demonstrating sensitive and robust quantitation of ORF2p for the first time.
Mobile DNA · Feb 6, 2025Peer-reviewedMolecular Biology