Martin S. Taylor

This study shows that cGAS deficiency in mice leads to premature aging through inflammation and de-repression of LINE1 elements.

The paper uses Nanopore long-read DNA sequencing to analyze retrotransposon activation in aged and Alzheimer's disease brains, identifying somatic insertions and epigenetic changes.

The paper quantifies viral mimicry in genomes across species and shows how repetitive elements maintain pathogen-like features under selection.

This paper develops targeted mass spectrometry assays to detect and quantify endogenous ORF1p and ORF2p proteins, demonstrating sensitive and robust quantitation of ORF2p for the first time.

This study identifies NDRG1 as a DNA repair protein that links pancreatic cancer stroma to chemoresistance by enhancing DNA damage repair through R-loop resolution.

The paper identifies distinct nuclear and cytoplasmic intermediates of LINE-1 retrotransposition using mass spectrometry and affinity purification.