Hua Liang Jiang

Repeats Mimic Pathogen-Associated Patterns Across a Vast Evolutionary Landscape

The paper quantifies viral mimicry in genomes across species and shows how repetitive elements maintain pathogen-like features under selection.

Targeted detection of endogenous LINE-1 proteins and ORF2p interactions

This paper develops targeted mass spectrometry assays to detect and quantify endogenous ORF1p and ORF2p proteins, demonstrating sensitive and robust quantitation of ORF2p for the first time.

Secretory trafficking maintains the organelle band for spindle separation during Arabidopsis meiosis

The paper identifies PELE as a protein that balances vacuolar and secretory trafficking to maintain the organelle band for spindle separation during Arabidopsis meiosis.

PDS5s control the Arabidopsis 3D genome by suppressing the formation of TAD-like domains

This study shows that PDS5 proteins in Arabidopsis prevent the formation of TAD-like domains in the 3D genome.

The plant nuclear lamina disassembles to regulate genome folding in stress conditions

The paper shows that the plant nuclear lamina disassembles under stress, altering chromatin organization and transcriptional profiles.

NCBP3 is a productive mRNP component

This study identifies NCBP3 as a component of an alternative CBC complex that interacts with EJC and TREX, supporting mRNA processing and nuclear export.

Dissection of purified LINE-1 reveals distinct nuclear and cytoplasmic intermediates

The paper identifies distinct nuclear and cytoplasmic intermediates of LINE-1 retrotransposition using mass spectrometry and affinity purification.