Author

Siyu Li

California State Polytechnic UniversityORCID 0000-0001-8468-5366Unclaimed ORCID profile · follow to get notified of new preprints

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Siyu Li3 papers · California State Polytechnic University

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

Roya ZandiiD· 2 shared Ajay GopinathaniD· 1 shared Alexandra N. Huang· 1 shared Arrmund Neal· 1 shared Denisse Cadena-López· 1 shared Duo XuiD· 1 shared Eric C. LiniD· 1 shared Hea Jin Hong· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Roya ZandiORCID

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2 papers

Recent·Most cited

Multiple protein-protein interactions drive the assembly and budding of the Chikungunya virion

Miguel Ángel Coronado-Ipiña, Shuyang Zhang, Siyu Li, Pedro G. Hernández‐Sánchez, Denisse Cadena-López, Vanessa Labrada‐Martagón, Ajay Gopinathan, Suchetana Mukhopadhyay, Roya Zandi, Mauricio Comas‐García

This study investigates Chikungunya virus assembly by combining simulations and experiments, showing that spike-spike interactions are critical for efficient budding and particle symmetry.

ACS Infectious Diseases · Jun 10, 2026Peer-reviewedBiophysics

Dynamics and Regulation of mRNA Cap Recognition by Human eIF4F

Hea Jin Hong, Matthew G. Guevara, Siyu Li, Yankang Liu, Alexandra N. Huang, Eric C. Lin, Arrmund Neal, Duo Xu, Rong Hai, Roya Zandi, Seán E. O’Leary

This study uses single-molecule fluorescence assays to show that eIF4G represses eIF4E-cap binding, while eIF4A relieves this repression, revealing new insights into eIF4F dynamics and mRNA recognition.

bioRxiv · Jun 26, 2025 · PreprintBiophysics