Desiccation-induced DNA damage facilitates drug resistance in Mycobacterium tuberculosis
Christopher D. Brown, Brendon M. Lee, Hannah M. Liu, Amy M. Wu, Andrea V. Tellez, Harry Zou, Prabhat Ranjan Singh, Kohta Saito, Saurabh Mishra, Megan Brown, A. M. Saleh, Narineh M. Odjourian, Melissa Cristaldo, Mingyu Gan, Qingyun Liu, , Kyu Young Rhee
This study shows desiccation-induced DNA damage in Mtb leads to mutations and drug resistance by affecting DNA repair and gene expression.
Nature Microbiology · Aug 26, 2026Peer-reviewedMicrobiology