Author

Xiuju Jiang

Weill Cornell MedicineORCID 0000-0002-9965-8771Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Carl NathaniD· 4 shared Adrián JinichiD· 2 shared Kyu Young RheeiD· 2 shared Prabhat Ranjan SinghiD· 2 shared Saurabh MishraiD· 2 shared Brian C. VanderVeniD· 1 shared Daniel J. PfauiD· 1 shared Dipak KathayatiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersMicrobiology

Carl NathanORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Effects of Exogenous Nitric Oxide Gas on Mycobacterium tuberculosis in vitro and in mice

Xiuju Jiang, Carl Nathan

This study investigates the effects of exogenous nitric oxide gas on Mycobacterium tuberculosis in vitro and in mice, finding bactericidal effects in vitro but limited anti-inflammatory benefits in vivo.

bioRxiv · Aug 19, 2026 · PreprintMicrobiology

Mycobacterium tuberculosis Genes Needed for Intra-alveolar Resuscitation After Airborne Transmission

Prabhat Ranjan Singh, Martin Gengenbacher, Saurabh Mishra, Adrián Jinich, Xiuju Jiang, Felipe Tsang, Melissa Cristaldo, Michael DeJesus, Kyu Young Rhee, Robert J. Kaner, Philip L. Leopold, Ronald G. Crystal, Dipak Kathayat, Brian C. VanderVen, Carl Nathan

The paper identifies genes in Mycobacterium tuberculosis essential for intra-alveolar survival after airborne transmission, revealing stage-specific roles in transmission.

bioRxiv · Sep 15, 2025 · PreprintMicrobiology

Mycobacterium tuberculosis, Mycobacterium kansasii and Rhodococcus equi induce macrophage necroptosis in the presence of a caspase inhibitor acting on a non-canonical target(s)

Rong Hu, Pei Li, Jie Han, Jiamin Huang, Garry Huang, Xiuju Jiang, Daniel J. Pfau, Guobao Li, Yinan Gong, Carl Nathan, Li Zhang

This study shows that z-VAD induces necroptosis in macrophages infected with Mtb, M. kansasii, and R. equi by acting on non-canonical targets, and MLKL deficiency reduces TB pathology in susceptible mice.

bioRxiv · Sep 2, 2025 · PreprintMicrobiology

Candidate transmission survival genome of Mycobacterium tuberculosis

Saurabh Mishra, Prabhat Ranjan Singh, Xiaoyi Hu, Landys A. Lopez Quezada, Adrián Jinich, Robin Jahn, Luc Geurts, Naijian Shen, Michael A. DeJesus, Travis E. Hartman, Kyu Young Rhee, Matthew Zimmerman, Veronique Anne Dartois, R. Mark Jones, Xiuju Jiang, , Carl Nathan

This study identifies a candidate transmission survival genome of Mycobacterium tuberculosis by exposing it to model aerosol fluid and analyzing gene contributions to survival during transmission.

Proceedings of the National Academy of Sciences · Mar 7, 2025Peer-reviewedMicrobiology