Author

Prabhat Ranjan Singh

Weill Cornell MedicineORCID 0009-0004-2995-1712Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:genome assembly· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Carl NathaniD· 3 shared Kyu Young RheeiD· 3 shared Saurabh MishraiD· 3 shared Adrián JinichiD· 2 shared Martin GengenbacheriD· 2 shared Melissa Cristaldo· 2 shared Xiuju JiangiD· 2 shared A. M. SalehiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMicrobiology

Carl NathanORCID

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Author profile →

3 papers

Recent·Most cited

Desiccation-induced DNA damage facilitates drug resistance in Mycobacterium tuberculosis

Christopher D. Brown, Brendon M. Lee, Hannah M. Liu, Amy M. Wu, Andrea V. Tellez, Harry Zou, Prabhat Ranjan Singh, Kohta Saito, Saurabh Mishra, Megan Brown, A. M. Saleh, Narineh M. Odjourian, Melissa Cristaldo, Mingyu Gan, Qingyun Liu, , Kyu Young Rhee

This study shows desiccation-induced DNA damage in Mtb leads to mutations and drug resistance by affecting DNA repair and gene expression.

Nature Microbiology · Aug 26, 2026Peer-reviewedMicrobiology

Mycobacterium tuberculosis Genes Needed for Intra-alveolar Resuscitation After Airborne Transmission

Prabhat Ranjan Singh, Martin Gengenbacher, Saurabh Mishra, Adrián Jinich, Xiuju Jiang, Felipe Tsang, Melissa Cristaldo, Michael DeJesus, Kyu Young Rhee, Robert J. Kaner, Philip L. Leopold, Ronald G. Crystal, Dipak Kathayat, Brian C. VanderVen, Carl Nathan

The paper identifies genes in Mycobacterium tuberculosis essential for intra-alveolar survival after airborne transmission, revealing stage-specific roles in transmission.

bioRxiv · Sep 15, 2025 · PreprintMicrobiology

Candidate transmission survival genome of Mycobacterium tuberculosis

Saurabh Mishra, Prabhat Ranjan Singh, Xiaoyi Hu, Landys A. Lopez Quezada, Adrián Jinich, Robin Jahn, Luc Geurts, Naijian Shen, Michael A. DeJesus, Travis E. Hartman, Kyu Young Rhee, Matthew Zimmerman, Veronique Anne Dartois, R. Mark Jones, Xiuju Jiang, , Carl Nathan

This study identifies a candidate transmission survival genome of Mycobacterium tuberculosis by exposing it to model aerosol fluid and analyzing gene contributions to survival during transmission.

Proceedings of the National Academy of Sciences · Mar 7, 2025Peer-reviewedMicrobiology