Altering cell size asymmetry in Drosophila neural stem cells creates supernumerary stem cells with limited lineage expansion potential
Melissa K. Delgado, J. Ian Hertzler, Sophia Jannetty, Mia Hoover, Chang Yin, Ilara Yilmaz, Danielle Vahdat, Adam von Barnau Sythoff, Jay Z. Parrish, Neda Bagheri, Clemens Cabernard
The paper investigates how altering cell size asymmetry in Drosophila neural stem cells affects their proliferation and lineage potential, finding increased stem cell pools but reduced lineage size and differentiation.
bioRxiv · Sep 26, 2025 · PreprintCell Biology