Author

Michael J. McLachlan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander Eckehart UrbaniD· 1 shared Alexis MitelpunktiD· 1 shared Bradley J. Swanson· 1 shared Bruce J. AronowiD· 1 shared Carolin PurmanniD· 1 shared ChangHui PakiD· 1 shared Douglas F. LevinsoniD· 1 shared Eric E. BardesiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alexander Eckehart UrbanORCID

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1 paper

Recent·Most cited

Cross-Platform Validation of Neurotransmitter Release Impairments in Schizophrenia Patient-Derived NRXN1-Mutant Neurons

ChangHui Pak, Tamás Dankó, Vincent R. Mirabella, Jinzhao Wang, Yingfei Liu, Madhuri Vangipuram, Sarah D. Grieder, Xianglong Zhang, Thomas Ward, Yu‐Wen Alvin Huang, Kang Jin, Phillip J. Dexheimer, Eric E. Bardes, Alexis Mitelpunkt, Junyi Ma, , Thomas Christian Südhof

This study validates that heterozygous NRXN1 deletions impair neurotransmitter release in human neurons across multiple labs, suggesting a human-specific synaptic dysfunction relevant for schizophrenia drug discovery.

Proceedings of the National Academy of Sciences · May 25, 2021Peer-reviewedNeuroscience